Cocaine-Dependent Acquisition of Locomotor Sensitization and Conditioned Place Preference Requires D1 Dopaminergic Signaling through a Cyclic AMP, NCS-Rapgef2, ERK, and Egr-1/Zif268 Pathway

Elucidation of the mechanism of dopamine signaling to ERK that underlies plasticity in dopamine D1 receptor-expressing neurons leading to acquired cocaine preference is incomplete. NCS-Rapgef2 is a novel cAMP effector, expressed in neuronal and endocrine cells in adult mammals, that is required for...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Jiang, Sunny Zhihong, Sweat, Sean, Dahlke, Sam P., Loane, Kathleen, Drossel, Gunner, Xu, Wenqin, Tejeda, Hugo A., Gerfen, Charles R., Eiden, Lee E.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2021
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7842751/
https://ncbi.nlm.nih.gov/pubmed/33268547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1497-20.2020
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