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In vitro AMPylation/Adenylylation of Alpha-synuclein by HYPE/FICD

One of the major histopathological hallmarks of Parkinson’s disease are Lewy bodies (LBs) –cytoplasmic inclusions, enriched with fibrillar forms of the presynaptic protein alpha-synuclein (α-syn). Progressive deposition of α-syn into LBs is enabled by its propensity to fibrillize into insoluble aggr...

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Dettagli Bibliografici
Pubblicato in:Bio Protoc
Autori principali: Camara, Ali, Sanyal, Anwesha, Dutta, Sayan, Rochet, Jean-Christophe, Mattoo, Seema
Natura: Artigo
Lingua:Inglês
Pubblicazione: Bio-Protocol 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7842671/
https://ncbi.nlm.nih.gov/pubmed/33659419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3760
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