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In vitro AMPylation/Adenylylation of Alpha-synuclein by HYPE/FICD
One of the major histopathological hallmarks of Parkinson’s disease are Lewy bodies (LBs) –cytoplasmic inclusions, enriched with fibrillar forms of the presynaptic protein alpha-synuclein (α-syn). Progressive deposition of α-syn into LBs is enabled by its propensity to fibrillize into insoluble aggr...
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| Veröffentlicht in: | Bio Protoc |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Bio-Protocol
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7842671/ https://ncbi.nlm.nih.gov/pubmed/33659419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3760 |
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