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Whole-cell and Perforated Patch-clamp Recordings from Acutely-isolated Murine Sino-atrial Node Cells

Cardiac pacemaker cells of the sino-atrial node are responsible for the initiation of the heart beat and express an array of ion channels. The patch-clamp technique is the gold standard method for investigating the function of ion channels expressed in electrically active cells. Conventional whole-c...

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Pubblicato in:Bio Protoc
Autori principali: Aziz, Qadeer, Nobles, Muriel, Tinker, Andrew
Natura: Artigo
Lingua:Inglês
Pubblicazione: Bio-Protocol 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7842407/
https://ncbi.nlm.nih.gov/pubmed/33654711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3478
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