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Flow Cytometry Measurement of Glucocerebrosidase Activity in Human Monocytes

Glucocerebrosidase (GCase) is an important enzyme for the metabolism of glycolipids. GCase enzyme deficiency is implicated in human disease and the efficient measurement of GCase activity is important for evaluating the efficacy of therapeutics targeting this enzyme. Existing approaches to measure G...

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Bibliographic Details
Published in:Bio Protoc
Main Authors: Hughes, Laura P., Halliday, Glenda M., Dzamko, Nicolas
Format: Artigo
Language:Inglês
Published: Bio-Protocol 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7842359/
https://ncbi.nlm.nih.gov/pubmed/33659542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3572
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