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 Knockout of the circadian gene, Per2, disrupts corticosterone secretion and results in depressive‐like behaviors and deficits in startle responses

BACKGROUND: The Period Circadian Regulator 2 (Per2) gene is important for the modulation of circadian rhythms that influence biological processes. Circadian control of the hypothalamus-pituitary-adrenal (HPA) axis is critical for regulation of hormones involved in the stress response. Dysregulation...

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Detalhes bibliográficos
Publicado no:BMC Neurosci
Main Authors: Russell, Ashley L., Miller, Lauren, Yi, Hannah, Keil, Rita, Handa, Robert J., Wu, T. John
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7841886/
https://ncbi.nlm.nih.gov/pubmed/33509094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-020-00607-y
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