Sacubitril/Valsartan Reduces Fibrosis and Alleviates High-Salt Diet-Induced HFpEF in Rats

Previous studies have confirmed the clinical efficacy of sacubitril/valsartan (Sac/Val) for the treatment of heart failure with reduced ejection fraction (HFrEF). However, the role of Sac/Val in heart failure with preserved ejection fraction (HFpEF) remains unclear. Sac/Val is a combination therapeu...

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Publicado en:Front Pharmacol
Autores principales: Zhang, Wenchao, Liu, Jianwei, Fu, Yang, Ji, Huifang, Fang, Zheyan, Zhou, Wanming, Fan, Huimin, Zhang, Yingxuan, Liao, Yan, Yang, Ting, Wang, Xiaolin, Yuan, Wanwan, Chen, Xiaoshu, Dong, Yi-fei
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7841406/
https://ncbi.nlm.nih.gov/pubmed/33519461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.600953
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