Liquid biopsy by combining 5-hydroxymethylcytosine signatures of plasma cell-free DNA and protein biomarkers for diagnosis and prognosis of hepatocellular carcinoma

BACKGROUND: Liquid biopsy based on 5-hydroxymethylcytosine (5hmC) signatures of plasma cell-free DNA (cfDNA) originating from tumor cells provides a novel approach for early diagnosis in hepatocellular carcinoma (HCC). Here, we sought to develop a reliable model using cfDNA 5hmC signatures and prote...

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Dettagli Bibliografici
Pubblicato in:ESMO Open
Autori principali: Cai, Z., Zhang, J., He, Y., Xia, L., Dong, X., Chen, G., Zhou, Y., Hu, X., Zhong, S., Wang, Y., Chen, H., Xie, D., Liu, X., Liu, J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7841321/
https://ncbi.nlm.nih.gov/pubmed/33508734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.esmoop.2020.100021
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