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APE1 distinguishes DNA substrates in exonucleolytic cleavage by induced space-filling
The exonuclease activity of Apurinic/apyrimidinic endonuclease 1 (APE1) is responsible for processing matched/mismatched terminus in various DNA repair pathways and for removing nucleoside analogs associated with drug resistance. To fill in the gap of structural basis for exonucleolytic cleavage, we...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7841161/ https://ncbi.nlm.nih.gov/pubmed/33504804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20853-2 |
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