Connective tissue growth factor promotes chemotaxis of preosteoblasts through integrin α5 and Ras during tensile force-induced intramembranous osteogenesis

In vertebrates, new bone formation via intramembranous osteogenesis is a critical biological event for development, remodeling, and fracture healing of bones. Chemotaxis of osteoblast lineage cells is an essential cellular process in new bone formation. Connective tissue growth factor (CTGF) is know...

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Publicado no:Sci Rep
Main Authors: Jiang, Wei, Takeshita, Nobuo, Maeda, Toshihiro, Sogi, Chisumi, Oyanagi, Toshihito, Kimura, Seiji, Yoshida, Michiko, Sasaki, Kiyo, Ito, Arata, Takano-Yamamoto, Teruko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7841149/
https://ncbi.nlm.nih.gov/pubmed/33504916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82246-9
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