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Detection of colorectal cancer in urine using DNA methylation analysis

Colorectal cancer (CRC) is the second leading cause for cancer-related death globally. Clinically, there is an urgent need for non-invasive CRC detection. This study assessed the feasibility of CRC detection by analysis of tumor-derived methylated DNA fragments in urine. Urine samples, including bot...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bach, S., Paulis, I., Sluiter, N. R., Tibbesma, M., Martin, I., van de Wiel, M. A., Tuynman, J. B., Bahce, I., Kazemier, G., Steenbergen, R. D. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840909/
https://ncbi.nlm.nih.gov/pubmed/33504902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81900-6
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