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Plasmonic nanoparticle amyloid corona for screening Aβ oligomeric aggregate-degrading drugs
The generation of toxic amyloid β (Aβ) oligomers is a central feature of the onset and progression of Alzheimer’s disease (AD). Drug discoveries for Aβ oligomer degradation have been hampered by the difficulty of Aβ oligomer purification and a lack of screening tools. Here, we report a plasmonic nan...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7840768/ https://ncbi.nlm.nih.gov/pubmed/33504788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20611-4 |
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