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Tumor-intrinsic and -extrinsic (immune) gene signatures robustly predict overall survival and treatment response in high grade serous ovarian cancer patients

In the present study, we developed a transcriptomic signature capable of predicting prognosis and response to primary therapy in high grade serous ovarian cancer (HGSOC). Proportional hazard analysis was performed on individual genes in the TCGA RNAseq data set containing 229 HGSOC patients. Ridge r...

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Pubblicato in:Am J Cancer Res
Autori principali: Mysona, David P, Tran, Lynn, Bai, Shan, dos Santos, Bruno, Ghamande, Sharad, Chan, John, She, Jin-Xiong
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840710/
https://ncbi.nlm.nih.gov/pubmed/33520368
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