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ABT-263 Reduces Hypertrophic Scars by Targeting Apoptosis of Myofibroblasts

Background: Inhibiting proliferation and inducing apoptosis of myofibroblasts is becoming one of the promising and effective ways to treat hypertrophic scar. ABT-263, as an orally bioavailable BCL-2 family inhibitor, has showed great antitumor characteristics by targeting tumor cell apoptosis. The o...

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Vydáno v:Front Pharmacol
Hlavní autoři: Yang, Xiaolan, Xiao, Yongqiang, Zhong, Chenjian, Shu, Futing, Xiao, Shichu, Zheng, Yongjun, Xia, Zhaofan
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840494/
https://ncbi.nlm.nih.gov/pubmed/33519480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.615505
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