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Mechanical Activation of MscL Revealed by a Locally Distributed Tension Molecular Dynamics Approach

Membrane tension perceived by mechanosensitive (MS) proteins mediates cellular responses to mechanical stimuli and osmotic stresses, and it also guides multiple biological functions including cardiovascular control and development. In bacteria, MS channels function as tension-activated pores limitin...

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Bibliographische Detailangaben
Veröffentlicht in:Biophys J
Hauptverfasser: Rajeshwar T., Rajitha, Anishkin, Andriy, Sukharev, Sergei, Vanegas, Juan M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840420/
https://ncbi.nlm.nih.gov/pubmed/33333032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.11.2274
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