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Predicting Genetic Variation Severity Using Machine Learning to Interpret Molecular Simulations
Distinct missense mutations in a specific gene have been associated with different diseases as well as differing severity of a disease. Current computational methods predict the potential pathogenicity of a missense variant but fail to differentiate between separate disease or severity phenotypes. W...
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| Pubblicato in: | Biophys J |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Biophysical Society
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7840418/ https://ncbi.nlm.nih.gov/pubmed/33333034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.12.002 |
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