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Analysis of Thyroid Hormone Receptor α-Knockout Tadpoles Reveals That the Activation of Cell Cycle Program Is Involved in Thyroid Hormone-Induced Larval Epithelial Cell Death and Adult Intestinal Stem Cell Development During Xenopus tropicalis Metamorphosis

Background: There are two highly conserved thyroid hormone (triiodothyronine [T3]) receptor (TR) genes, TRα and TRβ, in all vertebrates, and the expression of TRα but not TRβ is activated earlier than T3 synthesis during development. In human, high levels of T3 are present during the several months...

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Publicado en:Thyroid
Main Authors: Tanizaki, Yuta, Shibata, Yuki, Zhang, Hongen, Shi, Yun-Bo
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc., publishers 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840310/
https://ncbi.nlm.nih.gov/pubmed/32515287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2020.0022
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