A common variant in PNPLA3 is associated with age at diagnosis of NAFLD in patients from a multi-ethnic biobank

BACKGROUND & AIMS: The Ile138Met variant (rs738409) in the PNPLA3 gene has the largest effect on non-alcoholic fatty liver disease (NAFLD), increasing the risk of progression to severe forms of liver disease. It remains unknown if the variant plays a role in age of NAFLD onset. We aimed to deter...

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Detalhes bibliográficos
Publicado no:J Hepatol
Main Authors: Walker, Ryan W., Belbin, Gillian M., Sorokin, Elena P., Van Vleck, Tielman, Wojcik, Genevieve L., Moscati, Arden, Gignoux, Christopher R., Cho, Judy, Abul-Husn, Noura S., Nadkarni, Girish, Kenny, Eimear E., Loos, Ruth J.F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840172/
https://ncbi.nlm.nih.gov/pubmed/32145261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2020.01.029
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