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The structure of the actin filament uncapping complex mediated by twinfilin

Uncapping of actin filaments is essential for driving polymerization and depolymerization dynamics from capping protein–associated filaments; however, the mechanisms of uncapping leading to rapid disassembly are unknown. Here, we elucidated the x-ray crystal structure of the actin/twinfilin/capping...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Mwangangi, Dennis M., Manser, Edward, Robinson, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840138/
https://ncbi.nlm.nih.gov/pubmed/33571120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abd5271
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