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Evaluation of Inhaled Low Dose Formaldehyde Induced DNA adducts and DNA-protein cross-links by Liquid Chromatography-Tandem Mass Spectrometry

As a widespread industrial chemical, formaldehyde carcinogenicity has been highly controversial. Meanwhile, formaldehyde is an essential metabolite in all living cells. Previously, we have demonstrated exogenous formaldehyde causes DNA adducts in a nonlinear manner between 0.7 ppm to 15.2 ppm using...

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Detalhes bibliográficos
Publicado no:Arch Toxicol
Main Authors: Leng, Jiapeng, Liu, Chih-Wei, Hartwell, Hadley J., Yu, Rui, Lai, Yongquan, Bodnar, Wanda M., Lu, Kun, Swenberg, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839796/
https://ncbi.nlm.nih.gov/pubmed/30701286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-019-02393-x
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