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Boronic Acid‐Mediated Activity Control of Split 10–23 DNAzymes

The 10–23 DNAzyme is an artificially developed Mg(2+)‐dependent catalytic oligonucleotide that can cleave an RNA substrate in a sequence‐specific fashion. In this study, new split 10–23 DNAzymes made of two nonfunctional fragments, one of which carries a boronic acid group at its 5′ end, while the o...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Debiais, Mégane, Lelievre, Amandine, Vasseur, Jean‐Jacques, Müller, Sabine, Smietana, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839725/
https://ncbi.nlm.nih.gov/pubmed/33058268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202004227
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