Practical guidelines for monitoring and management of coagulopathy following tisagenlecleucel CAR T-cell therapy

Cytokine release syndrome (CRS) is a systemic inflammatory response associated with chimeric antigen receptor T-cell (CAR-T) therapies. In severe cases, CRS can be associated with coagulopathy and hypofibrinogenemia. We present our global multicenter experience with CRS-associated coagulopathy after...

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Bibliographic Details
Published in:Blood Adv
Main Authors: Buechner, Jochen, Grupp, Stephan A., Hiramatsu, Hidefumi, Teachey, David T., Rives, Susana, Laetsch, Theodore W., Yanik, Gregory A., Wood, Patricia, Awasthi, Rakesh, Yi, Lan, Chassot-Agostinho, Andrea, Eldjerou, Lamis K., De Moerloose, Barbara
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2021
Subjects:
Thrombosis and Hemostasis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839371/
https://ncbi.nlm.nih.gov/pubmed/33496754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002757
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