Adoptive therapy with CMV-specific cytotoxic T lymphocytes depends on baseline CD4(+) immunity to mediate durable responses

Adoptive cell therapy using cytomegalovirus (CMV)-specific cytotoxic T lymphocytes (CMV-CTLs) has demonstrated efficacy posttransplant. Despite the predicted limited engraftment of CMV-CTLs derived from third-party donors, partially matched third-party donor–derived CMV-CTLs have demonstrated simila...

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Dettagli Bibliografici
Pubblicato in:Blood Adv
Autori principali: Fabrizio, Vanessa A., Rodriguez-Sanchez, M. Irene, Mauguen, Audrey, Dahi, Parastoo B., Doubrovina, Ekaterina, O’Reilly, Richard J., Prockop, Susan E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2021
Soggetti:
Transplantation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839363/
https://ncbi.nlm.nih.gov/pubmed/33496746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002735
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