Heterozygous mutation SLFN14 K208N in mice mediates species-specific differences in platelet and erythroid lineage commitment

Schlafen 14 (SLFN14) has recently been identified as an endoribonuclease responsible for cleaving RNA to regulate and inhibit protein synthesis. Early studies revealed that members of the SLFN family are capable of altering lineage commitment during T-cell differentiation by using cell-cycle arrest...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Stapley, Rachel J., Smith, Christopher W., Haining, Elizabeth J., Bacon, Andrea, Lax, Sian, Pisareva, Vera P., Pisarev, Andrey V., Watson, Steve P., Khan, Abdullah O., Morgan, Neil V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2021
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839357/
https://ncbi.nlm.nih.gov/pubmed/33496736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002404
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