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Inhibition of Proliferation, Migration, and Invasion by Knockdown of Pyruvate Kinase-M2 (PKM2) in Ovarian Cancer SKOV3 and OVCAR3 Cells

Pyruvate kinase (PK) is a key enzyme in the process of glycolysis, catalyzing phosphoenolpyruvate (PEP) into pyruvate. Currently, PK isozyme type M2 (PKM2), one subtype of PK, has been proposed as a new tumor marker with high expression in various tumor tissues. Here we aimed to explore the effects...

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Publicat a:Oncol Res
Autors principals: Miao, Yi, Lu, Meng, Yan, Qin, Li, Shuangdi, Feng, Youji
Format: Artigo
Idioma:Inglês
Publicat: Cognizant Communication Corporation 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7838663/
https://ncbi.nlm.nih.gov/pubmed/28281967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096504016X14685034103671
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