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TROAP switches DYRK1 activity to drive hepatocellular carcinoma progression

Hepatocellular carcinoma (HCC) is one of the common malignancy and lacks effective therapeutic targets. Here, we demonstrated that ectopic expression of trophinin-associated protein (TROAP) dramatically drove HCC cell growth assessed by foci formation in monolayer culture, colony formation in soft a...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Li, Lei, Wei, Jia-Ru, Song, Ye, Fang, Shuo, Du, Yanyu, Li, Zhuo, Zeng, Ting-Ting, Zhu, Ying-Hui, Li, Yan, Guan, Xin-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7838256/
https://ncbi.nlm.nih.gov/pubmed/33500384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03422-3
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