Dihydropyridine Calcium Channel Blockers Suppress the Transcription of PD-L1 by Inhibiting the Activation of STAT1

Programmed death ligand 1 (PD-L1) which is upregulated in various epithelial tumors, plays a central role in the evasion of the immune system. In addition to monoclonal antibodies that blocking PD1/PD-L1 axis, finding small molecule compounds that can suppress PD-L1 expression might be another subst...

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Dades bibliogràfiques
Publicat a:Front Pharmacol
Autors principals: Pan, Xiaohui, Li, Run, Guo, Hongjie, Zhang, Wenxin, Xu, Xiaqing, Chen, Xi, Ding, Ling
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7838064/
https://ncbi.nlm.nih.gov/pubmed/33519429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.539261
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