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Essential statistical principles of clinical trials of pain treatments

This article presents an overview of fundamental statistical principles of clinical trials of pain treatments. Statistical considerations relevant to phase 2 proof of concept and phase 3 confirmatory randomized trials investigating efficacy and safety are discussed, including (1) research design; (2...

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Publicat a:Pain Rep
Autors principals: Dworkin, Robert H., Evans, Scott R., Mbowe, Omar, McDermott, Michael P.
Format: Artigo
Idioma:Inglês
Publicat: Wolters Kluwer 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7837867/
https://ncbi.nlm.nih.gov/pubmed/33521483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PR9.0000000000000863
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