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NADPH Oxidases Are Required for Full Platelet Activation In Vitro and Thrombosis In Vivo but Dispensable for Plasma Coagulation and Hemostasis
Using 3KO (triple NOX [NADPH oxidase] knockout) mice (ie, NOX1(−/−)/NOX2(−/−)/NOX4(−/−)), we aimed to clarify the role of this family of enzymes in the regulation of platelets in vitro and hemostasis in vivo. APPROACH AND RESULTS: 3KO mice displayed significantly reduced platelet superoxide radical...
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| Publicado no: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Lippincott Williams & Wilkins
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7837688/ https://ncbi.nlm.nih.gov/pubmed/33267663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.315565 |
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