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Deleting Mecp2 from the cerebellum rather than its neuronal subtypes causes a delay in motor learning in mice
Rett syndrome is a devastating childhood neurological disorder caused by mutations in MECP2. Of the many symptoms, motor deterioration is a significant problem for patients. In mice, deleting Mecp2 from the cortex or basal ganglia causes motor dysfunction, hypoactivity, and tremor, which are abnorma...
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| Publicat a: | eLife |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7837679/ https://ncbi.nlm.nih.gov/pubmed/33494858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.64833 |
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