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Decitabine and Cisplatin are Synergistic to Exert Anti-Tumor Effect on Gastric Cancer via Inducing Sox2 DNA Demethylation

BACKGROUND: Cisplatin is a vital chemotherapy regimen for gastric cancer (GC), while partial response is observed (approximately 40%) because of drug resistance. Thus, it is urgent to improve drug sensitivity to improve the therapeutic effect of cisplatin on GC. PURPOSE: The study was performed to e...

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Опубликовано в: :Onco Targets Ther
Главные авторы: Zhu, Zhipeng, Lin, Sihao, Wu, Xiaofang, Xu, Jiuhua, Li, Lulu, Ye, Weipeng, Li, Jiayi, Huang, Zhengjie
Формат: Artigo
Язык:Inglês
Опубликовано: Dove 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7837578/
https://ncbi.nlm.nih.gov/pubmed/33519210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S276168
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