Lymphocyte reconstitution after DMF discontinuation in clinical trial and real-world patients with MS

BACKGROUND: Delayed-release dimethyl fumarate (DMF) has demonstrated robust efficacy in treating patients with relapsing-remitting multiple sclerosis. Decreases in absolute lymphocyte count (ALC) are a well-known pharmacodynamic effect of DMF treatment, but lymphocyte recovery dynamics are not well...

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Dettagli Bibliografici
Pubblicato in:Neurol Clin Pract
Autori principali: Chan, Andrew, Rose, John, Alvarez, Enrique, Bar-Or, Amit, Butzkueven, Helmut, Fox, Robert J., Gold, Ralf, Gudesblatt, Mark, Haartsen, Jodi, Spelman, Tim, Wright, Katy, Ferraro, Diana, Sola, Patrizia, Hodgkinson, Suzanne, Kalincik, Tomas, Lechner-Scott, Jeannette, McGuigan, Christopher, Spach, Karen, Chen, Chongshu, Fam, Sami, Wu, Fan, Miller, Catherine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7837440/
https://ncbi.nlm.nih.gov/pubmed/33510947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/CPJ.0000000000000800
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