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The papain-like protease of coronaviruses cleaves ULK1 to disrupt host autophagy

The ongoing pandemic of COVID-19 alongside the outbreaks of SARS in 2003 and MERS in 2012 underscore the significance to understand betacoronaviruses as a global health challenge. SARS-CoV-2, the etiological agent for COVID-19, has infected over 50 million individuals’ worldwide with more than ∼1 mi...

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Podrobná bibliografie
Vydáno v:Biochem Biophys Res Commun
Hlavní autoři: Mohamud, Yasir, Xue, Yuan Chao, Liu, Huitao, Ng, Chen Seng, Bahreyni, Amirhossein, Jan, Eric, Luo, Honglin
Médium: Artigo
Jazyk:Inglês
Vydáno: The Authors. Published by Elsevier Inc. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7836930/
https://ncbi.nlm.nih.gov/pubmed/33450483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2020.12.091
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