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Differential Progression of Motor Dysfunction Between Male and Female Fragile X Premutation Carriers Reveals Novel Aspects of Sex-Specific Neural Involvement

Expansions of the CGG repeat in the non-coding segment of the FMR1 X-linked gene are associated with a variety of phenotypic changes. Large expansions (>200 repeats), which cause a severe neurodevelopmental disorder, the fragile x syndrome (FXS), are transmitted from the mothers carrying smaller,...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Loesch, Danuta Z., Tassone, Flora, Atkinson, Anna, Stimpson, Paige, Trost, Nicholas, Pountney, Dean L., Storey, Elsdon
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835843/
https://ncbi.nlm.nih.gov/pubmed/33511153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.577246
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