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Epigenetic Alterations in Renal Cell Cancer With TKIs Resistance: From Mechanisms to Clinical Applications

The appearance of tyrosine kinase inhibitors (TKIs) has been a major breakthrough in renal cell carcinoma (RCC) therapy. Unfortunately, a portion of patients with TKIs resistance experience disease progression after TKIs therapy. Epigenetic alterations play an important role in the development of TK...

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Détails bibliographiques
Publié dans:Front Genet
Auteurs principaux: Li, Qinhan, Zhang, Zhenan, Fan, Yu, Zhang, Qian
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835797/
https://ncbi.nlm.nih.gov/pubmed/33510766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.562868
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