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Genetic and Pharmacological Manipulations of Glyoxalase 1 Mediate Ethanol Withdrawal Seizure Susceptibility in Mice

Central nervous system (CNS) hyperexcitability is a clinically significant feature of acute ethanol withdrawal. There is evidence for a genetic contribution to withdrawal severity, but specific genetic risk factors have not been identified. The gene glyoxalase 1 (Glo1) has been previously implicated...

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Библиографические подробности
Опубликовано в: :Brain Sci
Главные авторы: Barkley-Levenson, Amanda M., Lee, Amy, Palmer, Abraham A.
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835754/
https://ncbi.nlm.nih.gov/pubmed/33478138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/brainsci11010127
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