Thy-1 (CD90)-Induced Metastatic Cancer Cell Migration and Invasion Are β3 Integrin-Dependent and Involve a Ca(2+)/P2X7 Receptor Signaling Axis

Cancer cell adhesion to the vascular endothelium is an important step in tumor metastasis. Thy-1 (CD90), a cell adhesion molecule expressed in activated endothelial cells, has been implicated in melanoma metastasis by binding to integrins present in cancer cells. However, the signaling pathway(s) tr...

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Dettagli Bibliografici
Pubblicato in:Front Cell Dev Biol
Autori principali: Brenet, Marianne, Martínez, Samuel, Pérez-Nuñez, Ramón, Pérez, Leonardo A., Contreras, Pamela, Díaz, Jorge, Avalos, Ana María, Schneider, Pascal, Quest, Andrew F. G., Leyton, Lisette
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Cell and Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835543/
https://ncbi.nlm.nih.gov/pubmed/33511115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.592442
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