ISEc69-Mediated Mobilization of the Colistin Resistance Gene mcr-2 in Escherichia coli

OBJECTIVES: The emergence of mobile colistin resistance genes has compromised the efficacy of the last resort antibiotic, colistin, in clinical treatment. The mcr-2 gene was first identified in Belgium in association with the insertion sequence ISEc69. However, the molecular mechanisms of mcr-2 mobi...

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Bibliographic Details
Published in:Front Microbiol
Main Authors: He, Yu-Zhang, Long, Teng-Fei, He, Bing, Li, Xing-Ping, Li, Gong, Chen, Liang, Liao, Xiao-Ping, Liu, Ya-Hong, Sun, Jian
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835479/
https://ncbi.nlm.nih.gov/pubmed/33510713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.564973
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