Pan-cancer analysis of transcripts encoding novel open-reading frames (nORFs) and their potential biological functions

Uncharacterized and unannotated open-reading frames, which we refer to as novel open reading frames (nORFs), may sometimes encode peptides that remain unexplored for novel therapeutic opportunities. To our knowledge, no systematic identification and characterization of transcripts encoding nORFs or...

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Pubblicato in:NPJ Genom Med
Autori principali: Erady, Chaitanya, Boxall, Adam, Puntambekar, Shraddha, Suhas Jagannathan, N., Chauhan, Ruchi, Chong, David, Meena, Narendra, Kulkarni, Apurv, Kasabe, Bhagyashri, Prathivadi Bhayankaram, Kethaki, Umrania, Yagnesh, Andreani, Adam, Nel, Jean, Wayland, Matthew T., Pina, Cristina, Lilley, Kathryn S., Prabakaran, Sudhakaran
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835362/
https://ncbi.nlm.nih.gov/pubmed/33495453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41525-020-00167-4
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