Epithelial expression of Gata4 and Sox2 regulates specification of the squamous–columnar junction via MAPK/ERK signaling in mice

The squamous–columnar junction (SCJ) is a boundary consisting of precisely positioned transitional epithelium between the squamous and columnar epithelium. Transitional epithelium is a hotspot for precancerous lesions, and is therefore clinically important; however, the origins and physiological pro...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Sankoda, Nao, Tanabe, Wataru, Tanaka, Akito, Shibata, Hirofumi, Woltjen, Knut, Chiba, Tsutomu, Haga, Hironori, Sakai, Yoshiharu, Mandai, Masaki, Yamamoto, Takuya, Yamada, Yasuhiro, Uemoto, Shinji, Kawaguchi, Yoshiya
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835245/
https://ncbi.nlm.nih.gov/pubmed/33495473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-20906-0
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