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Role of the C5a-C5a receptor axis in the inflammatory responses of the lungs after experimental polytrauma and hemorrhagic shock

Singular blockade of C5a in experimental models of sepsis is known to confer protection by rescuing lethality and decreasing pro-inflammatory responses. However, the role of inhibiting C5a has not been evaluated in the context of sterile systemic inflammatory responses, like polytrauma and hemorrhag...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Chakraborty, Shinjini, Winkelmann, Veronika Eva, Braumüller, Sonja, Palmer, Annette, Schultze, Anke, Klohs, Bettina, Ignatius, Anita, Vater, Axel, Fauler, Michael, Frick, Manfred, Huber-Lang, Markus
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835219/
https://ncbi.nlm.nih.gov/pubmed/33495506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79607-1
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