Atorvastatin improves motor function, anxiety and depression by NOX2-mediated autophagy and oxidative stress in MPTP-lesioned mice

Parkinson’s disease (PD) is a neurodegenerative disease caused by the loss of dopaminergic neurons. It is characterized by static tremors, stiffness, slow movements, and gait disturbances, but it is also accompanied by anxiety and depression. Our previous study showed that atorvastatin could reduce...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Yan, Junqiang, Huang, Jiarui, Liu, Anran, Wu, Jiannan, Fan, Hua, Shen, Mengmeng, Lai, Xiaoyi, Ma, Hongxia, Sun, Wenjie, Yang, Jianxue, Xu, Yunqi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835000/
https://ncbi.nlm.nih.gov/pubmed/33289703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202189
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