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Increased kynurenine-to-tryptophan ratio in the serum of patients infected with SARS-CoV2: An observational cohort study.()

Immune dysregulation is a hallmark of patients infected by SARS-CoV2 and the balance between immune reactivity and tolerance is a key determinant of all stages of infection, including the excessive inflammatory state causing the acute respiratory distress syndrome. The kynurenine pathway (KP) of try...

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Veröffentlicht in:Biochim Biophys Acta Mol Basis Dis
Hauptverfasser: Lionetto, Luana, Ulivieri, Martina, Capi, Matilde, De Bernardini, Donatella, Fazio, Francesco, Petrucca, Andrea, Pomes, Leda Marina, De Luca, Ottavia, Gentile, Giovanna, Casolla, Barbara, Curto, Martina, Salerno, Gerardo, Schillizzi, Serena, Torre, Maria Simona, Santino, Iolanda, Rocco, Monica, Marchetti, Paolo, Aceti, Antonio, Ricci, Alberto, Bonfini, Rita, Nicoletti, Ferdinando, Simmaco, Maurizio, Borro, Marina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier B.V. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7834629/
https://ncbi.nlm.nih.gov/pubmed/33338598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2020.166042
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