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Screening, simulation, and optimization design of small molecule inhibitors of the SARS-CoV-2 spike glycoprotein

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak is a public health emergency of international concern. The spike glycoprotein (S protein) of SARS-CoV-2 is a key target of antiviral drugs. Focusing on the existing S protein structure, molecular docking was used in this study...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sun, Chuancai, Zhang, Jian, Wei, Jiao, Zheng, Xiaoli, Zhao, Xianyang, Fang, Zengjun, Xu, Dongmei, Yuan, Huiqing, Liu, Yipeng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7833228/
https://ncbi.nlm.nih.gov/pubmed/33493227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0245975
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