Plasmodium falciparum erythrocyte membrane protein 1 variants induce cell swelling and disrupt the blood–brain barrier in cerebral malaria

Cerebral malaria (CM) is caused by the binding of Plasmodium falciparum–infected erythrocytes (IEs) to the brain microvasculature, leading to inflammation, vessel occlusion, and cerebral swelling. We have previously linked dual intercellular adhesion molecule-1 (ICAM-1)– and endothelial protein C re...

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Dades bibliogràfiques
Publicat a:J Exp Med
Autors principals: Adams, Yvonne, Olsen, Rebecca W., Bengtsson, Anja, Dalgaard, Nanna, Zdioruk, Mykola, Satpathi, Sanghamitra, Behera, Prativa K., Sahu, Praveen K., Lawler, Sean E., Qvortrup, Klaus, Wassmer, Samuel C., Jensen, Anja T.R.
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7833209/
https://ncbi.nlm.nih.gov/pubmed/33492344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20201266
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