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Repurposing approved drugs as potential inhibitors of 3CL-protease of SARS-CoV-2: Virtual screening and structure based drug design

3CL proteases (3CL(pro)) are only found in RNA viruses and have a central role in polyprotein processing during replication. Therefore, 3CL(pro) has emerged as promising drug target for therapeutic treatment of infections caused by Coronaviruses. In the light of the recent major outbreak of the SARS...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Comput Biol Chem
Egile nagusia: Meyer-Almes, Franz-Josef
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier Ltd. 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7832737/
https://ncbi.nlm.nih.gov/pubmed/32769050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.compbiolchem.2020.107351
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