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Repositioning chloroquine as antiviral prophylaxis against COVID-19: potential and challenges

The Coronavirus Disease 2019 (COVID-19) pandemic is advancing globally, and pharmaceutical prophylaxis is one solution. Here, we propose repositioning chloroquine (CQ) as prophylaxis against COVID-19. CQ blocks viral attachment and entry to host cells and demonstrates efficacy against a variety of v...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Drug Discov Today
Hauptverfasser: Chang, Raymond, Sun, Wei-Zen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Ltd. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7831558/
https://ncbi.nlm.nih.gov/pubmed/32629169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2020.06.030
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