Development of Three-Dimensional Human Intestinal Organoids as a Physiologically Relevant Model for Characterizing the Viral Replication Kinetics and Antiviral Susceptibility of Enteroviruses

Enteroviruses are important causes of hand, foot, and mouth disease, respiratory infections, and neurological infections in human. A major hurdle for the development of anti-enterovirus agents is the lack of physiologically relevant evaluation platforms that closely correlate with the in vivo state....

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Bibliographic Details
Published in:Biomedicines
Main Authors: Tsang, Jessica Oi-Ling, Zhou, Jie, Zhao, Xiaoyu, Li, Cun, Zou, Zijiao, Yin, Feifei, Yuan, Shuofeng, Yeung, Man-Lung, Chu, Hin, Chan, Jasper Fuk-Woo
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7831294/
https://ncbi.nlm.nih.gov/pubmed/33477611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9010088
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