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SuperTAD: robust detection of hierarchical topologically associated domains with optimized structural information

Topologically associating domains (TADs) are the organizational units of chromosome structures. TADs can contain TADs, thus forming a hierarchy. TAD hierarchies can be inferred from Hi-C data through coding trees. However, the current method for computing coding trees is not optimal. In this paper,...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Zhang, Yu Wei, Wang, Meng Bo, Li, Shuai Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7831269/
https://ncbi.nlm.nih.gov/pubmed/33494803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02234-6
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