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Mitochondrial haplogroup G is associated with nonalcoholic fatty liver disease, while haplogroup A mitigates the effects of PNPLA3
OBJECTIVES: Mitochondrial dysfunction plays a pivotal role in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). We hypothesized that mitochondrial DNA (mtDNA) haplogroups affect the risk of NAFLD in Han Chinese patients and interact with PNPLA3 genotypes. DESIGN: NAFLD and control patien...
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| Pubblicato in: | Endocrinol Diabetes Metab |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7831202/ https://ncbi.nlm.nih.gov/pubmed/33532620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/edm2.187 |
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