Delivery of miR-424-5p via Extracellular Vesicles Promotes the Apoptosis of MDA-MB-231 TNBC Cells in the Tumor Microenvironment

Programmed cell death ligand-1 (PD-L1) overexpressed on cancer cells has emerged as a key inhibitor that maintains the immunosuppressive microenvironment through its interaction with the PD-1 receptor in cancer. Here, we demonstrated that miR-424-5p delivery via extracellular vesicles (EVs) derived...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Zhou, Yueyuan, Yamamoto, Yusuke, Takeshita, Fumitaka, Yamamoto, Tomofumi, Xiao, Zhongdang, Ochiya, Takahiro
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7831022/
https://ncbi.nlm.nih.gov/pubmed/33467725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020844
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